Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

MIR-491 is commonly co-deleted with its adjacent CDKN2A on chromosome 9p21.3 in glioblastoma (GBM). However, it is not known whether deletion of MIR-491 is only a passenger event or plays an important role. Small-RNA sequencing of samples from GBM patients demonstrated that both mature products of M...

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Detalhes bibliográficos
Main Authors: Li, Xia, Liu, Yuexin, Granberg, Kirsi J., Wang, Qinhao, Moore, Lynette M., Ji, Ping, Gumin, Joy, Sulman, Erik P., Calin, George A., Haapasalo, Hannu, Nykter, Matti, Shmulevich, Ilya, Fuller, Gregory N., Lang, Frederick F., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205227/
https://ncbi.nlm.nih.gov/pubmed/24747968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.98
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