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Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1

Pellino proteins are RING E3 ubiquitin ligases involved in signaling events downstream of the Toll and interleukin-1 (IL-1) receptors, key initiators of innate immune and inflammatory responses. Pellino proteins associate with and ubiquitinate proteins in these pathways, including the interleukin-1...

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Autors principals: Lin, Chun-Chi, Huoh, Yu-San, Schmitz, Karl R., Jensen, Liselotte E., Ferguson, Kathryn M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205158/
https://ncbi.nlm.nih.gov/pubmed/19081057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.09.011
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