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Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1
Pellino proteins are RING E3 ubiquitin ligases involved in signaling events downstream of the Toll and interleukin-1 (IL-1) receptors, key initiators of innate immune and inflammatory responses. Pellino proteins associate with and ubiquitinate proteins in these pathways, including the interleukin-1...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205158/ https://ncbi.nlm.nih.gov/pubmed/19081057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.09.011 |
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