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The Pellino E3 Ubiquitin Ligases Recognize Specific Phosphothreonine Motifs and Have Distinct Substrate Specificities

[Image: see text] The four mammalian Pellinos (Pellinos 1, 2, 3a, and 3b) are E3 ubiquitin ligases that are emerging as critical mediators for a variety of immune signaling pathways, including those activated by Toll-like receptors, the T-cell receptor, and NOD2. It is becoming increasingly clear th...

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Detalhes bibliográficos
Main Authors: Huoh, Yu-San, Ferguson, Kathryn M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201300/
https://ncbi.nlm.nih.gov/pubmed/25027698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5005156
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