Poliovirus tropism and attenuation are determined after internal ribosome entry
Poliovirus replication is limited to a few organs, including the brain and spinal cord. This restricted tropism may be a consequence of organ-specific differences in translation initiation by the poliovirus internal ribosome entry site (IRES). A C-to-U mutation at base 472 in the IRES of the Sabin t...
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| 發表在: | J Clin Invest |
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| Principais autores: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15199409/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI21323 |
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