Inhibition of Corticosteroid-Binding Globulin Gene Expression by Glucocorticoids Involves C/EBPβ

Corticosteroid-binding globulin (CBG), a negative acute phase protein produced primarily in the liver, is responsible for the transport of glucocorticoids (GCs). It also modulates the bioavailability of GCs, as only free or unbound steroids are biologically active. Fluctuations in CBG levels therefo...

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Hauptverfasser: Verhoog, Nicolette, Allie-Reid, Fatima, Vanden Berghe, Wim, Smith, Carine, Haegeman, Guy, Hapgood, Janet, Louw, Ann
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205011/
https://ncbi.nlm.nih.gov/pubmed/25335188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110702
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