Abrogation of Glucocorticoid Receptor Dimerization Correlates with Dissociated Glucocorticoid Behavior of Compound A

Compound A (CpdA), a dissociated glucocorticoid receptor modulator, decreases corticosteroid-binding globulin (CBG), adrenocorticotropic hormone (ACTH), and luteneinizing hormone levels in rats. Whether this is due to transcriptional regulation by CpdA is not known. Using promoter reporter assays we...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Robertson, Steven, Allie-Reid, Fatima, Berghe, Wim Vanden, Visser, Koch, Binder, Anke, Africander, Donita, Vismer, Michael, De Bosscher, Karolien, Hapgood, Janet, Haegeman, Guy, Louw, Ann
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2010
Aiheet:
Gene Regulation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832957/
https://ncbi.nlm.nih.gov/pubmed/20037160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.087866
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