Abrogation of Glucocorticoid Receptor Dimerization Correlates with Dissociated Glucocorticoid Behavior of Compound A

Compound A (CpdA), a dissociated glucocorticoid receptor modulator, decreases corticosteroid-binding globulin (CBG), adrenocorticotropic hormone (ACTH), and luteneinizing hormone levels in rats. Whether this is due to transcriptional regulation by CpdA is not known. Using promoter reporter assays we...

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Dades bibliogràfiques
Autors principals: Robertson, Steven, Allie-Reid, Fatima, Berghe, Wim Vanden, Visser, Koch, Binder, Anke, Africander, Donita, Vismer, Michael, De Bosscher, Karolien, Hapgood, Janet, Haegeman, Guy, Louw, Ann
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832957/
https://ncbi.nlm.nih.gov/pubmed/20037160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.087866
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