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Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel
Ethanol alters nerve signalling by interacting with proteins in the central nervous system, particularly pentameric ligand-gated ion channels. A recent series of mutagenesis experiments on Gloeobacter violaceus ligand-gated ion channel, a prokaryotic member of this family, identified a single-site v...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4204805/ https://ncbi.nlm.nih.gov/pubmed/23591864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2682 |
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