Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides

The coronavirus SARS-CoV is the primary cause of the life-threatening severe acute respiratory syndrome (SARS). With the aim of developing therapeutic agents, we have tested peptides derived from the membrane-proximal (HR2) and membrane-distal (HR1) heptad repeat region of the spike protein as inhib...

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Hlavní autoři: Bosch, Berend Jan, Martina, Byron E. E., van der Zee, Ruurd, Lepault, Jean, Haijema, Bert Jan, Versluis, Cees, Heck, Albert J. R., de Groot, Raoul, Osterhaus, Albert D. M. E., Rottier, Peter J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC420415/
https://ncbi.nlm.nih.gov/pubmed/15150417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400576101
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