Nalaganje...
Synthesis and Incorporation of the Phosphoramidite Derivative of 2′-O-Photocaged 3′-S-Thioguanosine into Oligoribonucleotides: Substrate for Probing the Mechanism of RNA Catalysis
[Image: see text] Oligoribonucleotides containing 3′-S-phosphorothiolate linkages possess properties that can reveal deep mechanistic insights into ribozyme-catalyzed reactions. “Photocaged” 3′-S- RNAs could provide a strategy to stall reactions at the chemical stage and release them after assembly...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2014
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203407/ https://ncbi.nlm.nih.gov/pubmed/24635216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo4028374 |
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