FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation

AIM: To examine the effect of farnesoid X receptor (FXR) activation by GW4064 on endotoxin-induced hepatic inflammation in nonalcoholic fatty liver disease (NAFLD) and the underlying mechanism. METHODS: Six-week-old male C57BL/6 mice were fed a normal diet or a high-fat (HF) diet for 8 wk. HF diet-f...

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Detalhes bibliográficos
Principais autores: Yao, Jun, Zhou, Chun-Suo, Ma, Xiong, Fu, Bai-Qing, Tao, Li-Sheng, Chen, Miao, Xu, Ya-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202371/
https://ncbi.nlm.nih.gov/pubmed/25339829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i39.14430
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