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FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation
AIM: To examine the effect of farnesoid X receptor (FXR) activation by GW4064 on endotoxin-induced hepatic inflammation in nonalcoholic fatty liver disease (NAFLD) and the underlying mechanism. METHODS: Six-week-old male C57BL/6 mice were fed a normal diet or a high-fat (HF) diet for 8 wk. HF diet-f...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Baishideng Publishing Group Inc
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4202371/ https://ncbi.nlm.nih.gov/pubmed/25339829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i39.14430 |
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