Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas

The intrinsic signaling cascades and cell states associated with the Glioma CpG Island Methylator Phenotype (G-CIMP) remain poorly understood. Using published mRNA signatures associated with EGFR activation, we demonstrate that G-CIMP+ tumors harbor decreased EGFR signaling using three independent d...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Li, Jie, Taich, Zachary J., Goyal, Amit, Gonda, David, Akers, Johnny, Adhikari, Bandita, Patel, Kunal, Vandenberg, Scott, Yan, Wei, Bao, Zhaoshi, Carter, Bob S., Wang, Renzhi, Mao, Ying, Jiang, Tao, Chen, Clark C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2014
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202127/
https://ncbi.nlm.nih.gov/pubmed/25277177
Etiketler: Etiketle
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