Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas

The intrinsic signaling cascades and cell states associated with the Glioma CpG Island Methylator Phenotype (G-CIMP) remain poorly understood. Using published mRNA signatures associated with EGFR activation, we demonstrate that G-CIMP+ tumors harbor decreased EGFR signaling using three independent d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Jie, Taich, Zachary J., Goyal, Amit, Gonda, David, Akers, Johnny, Adhikari, Bandita, Patel, Kunal, Vandenberg, Scott, Yan, Wei, Bao, Zhaoshi, Carter, Bob S., Wang, Renzhi, Mao, Ying, Jiang, Tao, Chen, Clark C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2014
Gaiak:
Priority Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202127/
https://ncbi.nlm.nih.gov/pubmed/25277177
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