Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas

OBJECTIVE: To identify novel epigenetic signatures that could provide predictive information that is complementary to promoter methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) gene for predicting temozolomide (TMZ) response, among glioblastomas (GBMs) without glioma-CpGs isla...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Yin, An-An, He, Ya-Long, Etcheverry, Amandine, Liu, Yu-He, Aubry, Marc, Barnholtz-Sloan, Jill, Liu, Bo-Lin, Mosser, Jean, Lu, Zi-Fan, Zhang, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515684/
https://ncbi.nlm.nih.gov/pubmed/31088577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0670-9
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