Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

Glioblastoma remains one of the deadliest of human cancers, with most patients succumbing to the disease within two years of diagnosis. The available data suggest that simultaneous inactivation of critical nodes within the glioblastoma molecular circuitry will be required for meaningful clinical eff...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Li, Jie, Zhu, Shan, Kozono, David, Ng, Kimberly, Futalan, Diahnn, Shen, Ying, Akers, Johnny C., Steed, Tyler, Kushwaha, Deepa, Schlabach, Michael, Carter, Bob S., Kwon, Chang-Hyuk, Furnari, Frank, Cavenee, Webster, Elledge, Stephen, Chen, Clark C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Priority Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011590/
https://ncbi.nlm.nih.gov/pubmed/24658464
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge