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Overexpression of histone deacetylases in cancer cells is controlled by interplay of transcription factors and epigenetic modulators

Histone deacetylases (HDACs) that deacetylate histone and nonhistone proteins play crucial roles in a variety of cellular processes. The overexpression of HDACs is reported in many cancer types and is directly linked to accelerated cell proliferation and survival. However, little is known about how...

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Main Authors: Yang, Hui, Salz, Tal, Zajac-Kaye, Maria, Liao, Daiqing, Huang, Suming, Qiu, Yi
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202103/
https://ncbi.nlm.nih.gov/pubmed/24948597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-250654
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