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FOXO3-mTOR Metabolic Cooperation in the Regulation of Erythroid Cell Maturation and Homeostasis

Ineffective erythropoiesis is observed in many erythroid disorders including β-thalassemia and anemia of chronic disease in which increased production of erythroblasts that fail to mature exacerbate the underlying anemias. As loss of the transcription factor FOXO3 results in erythroblast abnormaliti...

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Hlavní autoři: Zhang, Xin, Campreciós, Genís, Rimmelé, Pauline, Liang, Raymond, Yalcin, Safak, Mungamuri, Sathish Kumar, Barminko, Jeffrey, D’Escamard, Valentina, Baron, Margaret H., Brugnara, Carlo, Papatsenko, Dmitri, Rivella, Stefano, Ghaffari, Saghi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201594/
https://ncbi.nlm.nih.gov/pubmed/24966026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23786
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