FOXO3-mTOR Metabolic Cooperation in the Regulation of Erythroid Cell Maturation and Homeostasis

Ineffective erythropoiesis is observed in many erythroid disorders including β-thalassemia and anemia of chronic disease in which increased production of erythroblasts that fail to mature exacerbate the underlying anemias. As loss of the transcription factor FOXO3 results in erythroblast abnormaliti...

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Main Authors: Zhang, Xin, Campreciós, Genís, Rimmelé, Pauline, Liang, Raymond, Yalcin, Safak, Mungamuri, Sathish Kumar, Barminko, Jeffrey, D’Escamard, Valentina, Baron, Margaret H., Brugnara, Carlo, Papatsenko, Dmitri, Rivella, Stefano, Ghaffari, Saghi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201594/
https://ncbi.nlm.nih.gov/pubmed/24966026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23786
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