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Interstrand Cross-Link and Bioconjugate Formation in RNA from a Modified Nucleotide

[Image: see text] RNA oligonucleotides containing a phenyl selenide derivative of 5-methyluridine were chemically synthesized by solid-phase synthesis. The phenyl selenide is rapidly converted to an electrophilic, allylic phenyl seleneate under mild oxidative conditions. The phenyl seleneate yields...

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Autores principales: Sloane, Jack L., Greenberg, Marc M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201359/
https://ncbi.nlm.nih.gov/pubmed/25295850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo501982r
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