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A Double-Hotdog with a New Trick: Structure and Mechanism of the trans-Acyltransferase Polyketide Synthase Enoyl-isomerase

[Image: see text] Many polyketide natural products exhibit invaluable medicinal properties, yet much remains to be understood regarding the machinery responsible for their biosynthesis. The recently discovered trans-acyltransferase polyketide synthases employ processing enzymes that catalyze modific...

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Autors principals: Gay, Darren C., Spear, Philip J., Keatinge-Clay, Adrian T.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201341/
https://ncbi.nlm.nih.gov/pubmed/25089587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500459b
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