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Constitutive p21-activated Kinase (PAK) Activation in Breast Cancer Cells as a Result of Mislocalization of PAK to Focal Adhesions

Cytoskeletal remodeling is critical for cell adhesion, spreading, and motility. p21-activated kinase (PAK), an effector molecule of the Rho GTPases Rac and Cdc42, has been implicated in cytoskeletal remodeling and cell motility. PAK kinase activity and subcellular distribution are tightly regulated...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Cell
Prif Awduron: Stofega, Mary R., Sanders, Luraynne C., Gardiner, Elisabeth M., Bokoch, Gary M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Cell Biology 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420118/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047871/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-08-0604
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