Constitutive p21-activated Kinase (PAK) Activation in Breast Cancer Cells as a Result of Mislocalization of PAK to Focal Adhesions

Cytoskeletal remodeling is critical for cell adhesion, spreading, and motility. p21-activated kinase (PAK), an effector molecule of the Rho GTPases Rac and Cdc42, has been implicated in cytoskeletal remodeling and cell motility. PAK kinase activity and subcellular distribution are tightly regulated...

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Dades bibliogràfiques

Publicat a:	Mol Biol Cell
Autors principals:	Stofega, Mary R., Sanders, Luraynne C., Gardiner, Elisabeth M., Bokoch, Gary M.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Cell Biology 2004
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-08-0604
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