Constitutive p21-activated Kinase (PAK) Activation in Breast Cancer Cells as a Result of Mislocalization of PAK to Focal Adhesions

Cytoskeletal remodeling is critical for cell adhesion, spreading, and motility. p21-activated kinase (PAK), an effector molecule of the Rho GTPases Rac and Cdc42, has been implicated in cytoskeletal remodeling and cell motility. PAK kinase activity and subcellular distribution are tightly regulated...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Stofega, Mary R., Sanders, Luraynne C., Gardiner, Elisabeth M., Bokoch, Gary M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2004
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-08-0604
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