Constitutive p21-activated Kinase (PAK) Activation in Breast Cancer Cells as a Result of Mislocalization of PAK to Focal Adhesions

Cytoskeletal remodeling is critical for cell adhesion, spreading, and motility. p21-activated kinase (PAK), an effector molecule of the Rho GTPases Rac and Cdc42, has been implicated in cytoskeletal remodeling and cell motility. PAK kinase activity and subcellular distribution are tightly regulated...

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Bibliografiske detaljer

Udgivet i:	Mol Biol Cell
Principais autores:	Stofega, Mary R., Sanders, Luraynne C., Gardiner, Elisabeth M., Bokoch, Gary M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Cell Biology 2004
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-08-0604
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