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Comparison of the mammalian insulin signalling pathway to invertebrates in the context of FOXO-mediated ageing
Motivation: A large number of experimental studies on ageing focus on the effects of genetic perturbations of the insulin/insulin-like growth factor signalling pathway (IIS) on lifespan. Short-lived invertebrate laboratory model organisms are extensively used to quickly identify ageing-related genes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201157/ https://ncbi.nlm.nih.gov/pubmed/25064569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu493 |
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