Role of Tyrosine Kinase Inhibitors in the Management of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

The Philadelphia chromosome is the most common cytogenetic abnormality found in adult patients diagnosed with acute lymphoblastic leukemia. The result of this abnormality is the BCR-ABL protein, a constitutively active kinase involved in cell signaling and survival. When managed with multiagent chem...

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Detaylı Bibliyografya
Asıl Yazarlar: Mathisen, Michael S., O’Brien, Susan, Thomas, Deborah, Cortes, Jorge, Kantarjian, Hagop, Ravandi, Farhad
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201047/
https://ncbi.nlm.nih.gov/pubmed/21660654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11899-011-0093-y
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