Philadelphia-Positive Acute Lymphoblastic Leukemia: Current Treatment Options

The Philadelphia chromosome (Ph), t(9;22), is seen in about 20 % to 30 % of adults diagnosed with acute lymphoblastic leukemia (ALL). It has been associated with poorer prognosis compared with Ph-negative ALL. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL oncogenic protein from this transl...

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Bibliografiske detaljer
Main Authors: Liu-Dumlao, Theresa, Kantarjian, Hagop, Thomas, Deborah A., O’Brien, Susan, Ravandi, Farhad
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199301/
https://ncbi.nlm.nih.gov/pubmed/22669492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-012-0247-7
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