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Philadelphia-Positive Acute Lymphoblastic Leukemia: Current Treatment Options
The Philadelphia chromosome (Ph), t(9;22), is seen in about 20 % to 30 % of adults diagnosed with acute lymphoblastic leukemia (ALL). It has been associated with poorer prognosis compared with Ph-negative ALL. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL oncogenic protein from this transl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199301/ https://ncbi.nlm.nih.gov/pubmed/22669492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-012-0247-7 |
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