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Philadelphia-Positive Acute Lymphoblastic Leukemia: Current Treatment Options

The Philadelphia chromosome (Ph), t(9;22), is seen in about 20 % to 30 % of adults diagnosed with acute lymphoblastic leukemia (ALL). It has been associated with poorer prognosis compared with Ph-negative ALL. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL oncogenic protein from this transl...

詳細記述

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書誌詳細
主要な著者: Liu-Dumlao, Theresa, Kantarjian, Hagop, Thomas, Deborah A., O’Brien, Susan, Ravandi, Farhad
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199301/
https://ncbi.nlm.nih.gov/pubmed/22669492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-012-0247-7
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