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Mycobacterium tuberculosis Promotes Anti-apoptotic Activity of the Macrophage by PtpA Protein-dependent Dephosphorylation of Host GSK3α

Mycobacterium tuberculosis tyrosine phosphatase PtpA inhibits two key cellular events in macrophages required for the elimination of invading organisms, phagosome acidification, and maturation. Kinome analysis revealed multiple PtpA-dependent changes to the phosphorylation status of macrophage prote...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Poirier, Valérie, Bach, Horacio, Av-Gay, Yossef
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200286/
https://ncbi.nlm.nih.gov/pubmed/25187516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582502
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