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Mycobacterium tuberculosis Promotes Anti-apoptotic Activity of the Macrophage by PtpA Protein-dependent Dephosphorylation of Host GSK3α

Mycobacterium tuberculosis tyrosine phosphatase PtpA inhibits two key cellular events in macrophages required for the elimination of invading organisms, phagosome acidification, and maturation. Kinome analysis revealed multiple PtpA-dependent changes to the phosphorylation status of macrophage prote...

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Autors principals: Poirier, Valérie, Bach, Horacio, Av-Gay, Yossef
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200286/
https://ncbi.nlm.nih.gov/pubmed/25187516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582502
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