Mycobacterium tuberculosis Promotes Anti-apoptotic Activity of the Macrophage by PtpA Protein-dependent Dephosphorylation of Host GSK3α

Mycobacterium tuberculosis tyrosine phosphatase PtpA inhibits two key cellular events in macrophages required for the elimination of invading organisms, phagosome acidification, and maturation. Kinome analysis revealed multiple PtpA-dependent changes to the phosphorylation status of macrophage prote...

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Hlavní autoři: Poirier, Valérie, Bach, Horacio, Av-Gay, Yossef
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200286/
https://ncbi.nlm.nih.gov/pubmed/25187516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582502
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