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Large Conductance Voltage- and Ca(2+)-gated Potassium (BK) Channel β4 Subunit Influences Sensitivity and Tolerance to Alcohol by Altering Its Response to Kinases

Tolerance is a well described component of alcohol abuse and addiction. The large conductance voltage- and Ca(2+)-gated potassium channel (BK) has been very useful for studying molecular tolerance. The influence of association with the β4 subunit can be observed at the level of individual channels,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Velázquez-Marrero, Cristina, Seale, Garrett E., Treistman, Steven N., Martin, Gilles E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200277/
https://ncbi.nlm.nih.gov/pubmed/25190810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604306
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