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Large Conductance Voltage- and Ca(2+)-gated Potassium (BK) Channel β4 Subunit Influences Sensitivity and Tolerance to Alcohol by Altering Its Response to Kinases

Tolerance is a well described component of alcohol abuse and addiction. The large conductance voltage- and Ca(2+)-gated potassium channel (BK) has been very useful for studying molecular tolerance. The influence of association with the β4 subunit can be observed at the level of individual channels,...

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Autori principali: Velázquez-Marrero, Cristina, Seale, Garrett E., Treistman, Steven N., Martin, Gilles E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200277/
https://ncbi.nlm.nih.gov/pubmed/25190810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604306
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