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An alcohol-sensing site in the calcium- and voltage-gated, large conductance potassium (BK) channel
Ethanol alters BK (slo1) channel function leading to perturbation of physiology and behavior. Site(s) and mechanism(s) of ethanol–BK channel interaction are unknown. We demonstrate that ethanol docks onto a water-accessible site that is strategically positioned between the slo1 calcium-sensors and g...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078796/ https://ncbi.nlm.nih.gov/pubmed/24927535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317363111 |
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