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Selective inhibitors of nuclear export (SINE)– a novel class of anti-cancer agents
Dysregulation of the nucleo-cytoplasmic transport of proteins plays an important role in carcinogenesis. The nuclear export of proteins depends on the activity of transport proteins, exportins. Exportins belong to the karyopherin β superfamily. Exportin-1 (XPO1), also known as chromosomal region mai...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200201/ https://ncbi.nlm.nih.gov/pubmed/25316614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0078-0 |
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