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Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
Histone deacetylases (HDACs) can regulate expression of tumor suppressor genes and activities of transcriptional factors involved in both cancer initiation and progression through alteration of either DNA or the structural components of chromatin. Recently, the role of gene repression through modula...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827364/ https://ncbi.nlm.nih.gov/pubmed/20132536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-3-5 |
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