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New clinical developments in histone deacetylase inhibitors for epigenetic therapy of cancer
DNA methylation and histone acetylation are two well known epigenetic chromatin modifications. Epigenetic agents leading to DNA hypomethylation and histone hyperacetylation have been approved for treatment of hematological disorders. The first histone deacetylase inhibitor, vorinostat, has been lice...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695818/ https://ncbi.nlm.nih.gov/pubmed/19486511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-2-22 |
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