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SINE (selective inhibitor of nuclear export) – translational science in a new class of anti-cancer agents

Regulation of protein trafficking between the nucleus and cytoplasm represents a novel control point for antineoplastic intervention. Several proteins involved with cellular growth and survival depend on precise and timely positioning within the cell to fulfill their functions, and the nuclear membr...

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Библиографические подробности
Главный автор: Gerecitano, John
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197302/
https://ncbi.nlm.nih.gov/pubmed/25281264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0067-3
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