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SINE (selective inhibitor of nuclear export) – translational science in a new class of anti-cancer agents

Regulation of protein trafficking between the nucleus and cytoplasm represents a novel control point for antineoplastic intervention. Several proteins involved with cellular growth and survival depend on precise and timely positioning within the cell to fulfill their functions, and the nuclear membr...

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Detalhes bibliográficos
Autor principal: Gerecitano, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197302/
https://ncbi.nlm.nih.gov/pubmed/25281264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0067-3
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