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MicroRNA-188 suppresses G(1)/S transition by targeting multiple cyclin/CDK complexes
BACKGROUND: Accelerated cell cycle progression is the common feature of most cancers. MiRNAs can act as oncogenes or tumor suppressors by directly modulating cell cycle machinery. It has been shown that miR-188 is upregulated in UVB-irradiated mouse skin and human nasopharyngeal carcinoma CNE cells...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200121/ https://ncbi.nlm.nih.gov/pubmed/25304455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0066-6 |
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