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DC-HIL-expressing Myelomonocytic Cells Are Critical Promoters of Melanoma Growth

A major barrier to successful cancer immunotherapy is the tumor’s ability to induce T-cell tolerance by exploiting host regulatory mechanisms. Having discovered the DC-HIL receptor, which inhibits T-cell responses by binding to syndecan-4 on effector T-cells, we posited the DC-HIL/syndecan-4 pathway...

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Detalhes bibliográficos
Main Authors: Chung, Jin-Sung, Tamura, Kyoichi, Cruz, Ponciano D., Ariizumi, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199867/
https://ncbi.nlm.nih.gov/pubmed/24936834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.254
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