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The DC-HIL/Syndecan-4 Pathway Regulates Autoimmune Responses Through Myeloid-derived Suppressor Cells

Having discovered that the DC-HIL receptor on antigen presenting cells inhibits T cell activation by binding to syndecan-4 (SD-4) on T cells, we hypothesized that the DC-HIL/SD-4 pathway may regulate autoimmune responses. Using experimental autoimmune encephalomyelitis (EAE) as a disease model, we n...

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Detalhes bibliográficos
Main Authors: Chung, Jin-Sung, Tamura, Kyoichi, Akiyoshi, Hideo, Cruz, Ponciano D., Ariizumi, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957202/
https://ncbi.nlm.nih.gov/pubmed/24516197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301857
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