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The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease

Acute graft-versus-host disease (GVHD) is the most important cause of mortality after allogeneic haematopoietic stem cell transplantation. Allo-reactive T cells are the major mediators of GVHD and the process is regulated by positive and negative regulators on antigen-presenting cells (APC). Because...

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Detalhes bibliográficos
Main Authors: Chung, Jin-Sung, Tomihari, Mizuki, Tamura, Kyoichi, Kojima, Tetsuhito, Cruz, Ponciano D, Ariizumi, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575770/
https://ncbi.nlm.nih.gov/pubmed/23113638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12027
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