The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

Destruction of the pulmonary epithelium is a major feature of lung diseases caused by the mould pathogen Aspergillus fumigatus. Although it is widely postulated that tissue invasion is governed by fungal proteases, A. fumigatus mutants lacking individual or multiple enzymes remain fully invasive, su...

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Main Authors: Bertuzzi, Margherita, Schrettl, Markus, Alcazar-Fuoli, Laura, Cairns, Timothy C., Muñoz, Alberto, Walker, Louise A., Herbst, Susanne, Safari, Maryam, Cheverton, Angela M., Chen, Dan, Liu, Hong, Saijo, Shinobu, Fedorova, Natalie D., Armstrong-James, Darius, Munro, Carol A., Read, Nick D., Filler, Scott G., Espeso, Eduardo A., Nierman, William C., Haas, Hubertus, Bignell, Elaine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199764/
https://ncbi.nlm.nih.gov/pubmed/25329394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004413
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