The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

Destruction of the pulmonary epithelium is a major feature of lung diseases caused by the mould pathogen Aspergillus fumigatus. Although it is widely postulated that tissue invasion is governed by fungal proteases, A. fumigatus mutants lacking individual or multiple enzymes remain fully invasive, su...

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Hauptverfasser: Bertuzzi, Margherita, Schrettl, Markus, Alcazar-Fuoli, Laura, Cairns, Timothy C., Muñoz, Alberto, Walker, Louise A., Herbst, Susanne, Safari, Maryam, Cheverton, Angela M., Chen, Dan, Liu, Hong, Saijo, Shinobu, Fedorova, Natalie D., Armstrong-James, Darius, Munro, Carol A., Read, Nick D., Filler, Scott G., Espeso, Eduardo A., Nierman, William C., Haas, Hubertus, Bignell, Elaine M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199764/
https://ncbi.nlm.nih.gov/pubmed/25329394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004413
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