The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

Histone variant H3.3 is deposited in chromatin at active sites, telomeres, and pericentric heterochromatin by distinct chaperones, but the mechanisms of regulation and coordination of chaperone-mediated H3.3 loading remain largely unknown. We show here that the chromatin-associated oncoprotein DEK r...

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Hlavní autoři: Ivanauskiene, Kristina, Delbarre, Erwan, McGhie, James D., Küntziger, Thomas, Wong, Lee H., Collas, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199371/
https://ncbi.nlm.nih.gov/pubmed/25049225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.173831.114
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