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DAXX-dependent supply of soluble (H3.3–H4) dimers to PML bodies pending deposition into chromatin
Replication-independent chromatin deposition of histone variant H3.3 is mediated by several chaperones. We report a multistep targeting of newly synthesized epitope-tagged H3.3 to chromatin via PML bodies. H3.3 is recruited to PML bodies in a DAXX-dependent manner, a process facilitated by ASF1A. DA...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589533/ https://ncbi.nlm.nih.gov/pubmed/23222847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.142703.112 |
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