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The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity
Histone variant H3.3 is deposited in chromatin at active sites, telomeres, and pericentric heterochromatin by distinct chaperones, but the mechanisms of regulation and coordination of chaperone-mediated H3.3 loading remain largely unknown. We show here that the chromatin-associated oncoprotein DEK r...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199371/ https://ncbi.nlm.nih.gov/pubmed/25049225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.173831.114 |
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