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The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

Histone variant H3.3 is deposited in chromatin at active sites, telomeres, and pericentric heterochromatin by distinct chaperones, but the mechanisms of regulation and coordination of chaperone-mediated H3.3 loading remain largely unknown. We show here that the chromatin-associated oncoprotein DEK r...

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Detalhes bibliográficos
Main Authors: Ivanauskiene, Kristina, Delbarre, Erwan, McGhie, James D., Küntziger, Thomas, Wong, Lee H., Collas, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199371/
https://ncbi.nlm.nih.gov/pubmed/25049225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.173831.114
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