Reciprocal Regulation of miR-122 and c-Myc in Hepatocellular Cancer: Role of E2F1 and TFDP2

c-Myc is a well-known oncogene frequently upregulated in different malignancies, whereas liver specific miR-122, a bona fide tumor suppressor, is downregulated in hepatocellular cancer (HCC). Here, we explored the underlying mechanism of reciprocal regulation of these two genes. Real-time RT-PCR and...

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Autori principali: Wang, Bo, Hsu, Shu-hao, Wang, Xinmei, Kutay, Huban, Bid, Hemant Kumar, Yu, Jianhua, Ganju, Ramesh, Jacob, Samson, Yuneva, Mariia, Ghoshal, Kalpana
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199239/
https://ncbi.nlm.nih.gov/pubmed/24038073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26712
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