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Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
miR-122, an abundant liver-specific microRNA (miRNA), regulates cholesterol metabolism and promotes hepatitis C virus (HCV) replication. Reduced miR-122 expression in hepatocellular carcinoma (HCC) correlates with metastasis and poor prognosis. Nevertheless, the consequences of sustained loss of fun...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408748/ https://ncbi.nlm.nih.gov/pubmed/22820288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63539 |
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